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. 2023 Jan 16;24(2):1797. doi: 10.3390/ijms24021797

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Kaplan-Meier curve of combined effect of rs2395185 and rs2097432 on failure of anti-TNF drugs. (a) Patients carrying a low-risk haplotype (orange) or any other haplotypes (green); (b) Patients carrying a low-risk haplotype (orange), a medium-risk haplotype (blue), or a high-risk haplotype (green). Genotype comparisons and p values for the univariate analysis (KM p value) and multivariate analysis (Cox p value) analyses are presented alongside Kaplan-Meier curves. Significant p values are marked in bold. * Reference genotypes.