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. 2023 Jan 12;15(1):274. doi: 10.3390/pharmaceutics15010274

Figure 16.

Figure 16

Scheme showing preparation of ONP@ZnO2@ZIF-67 and the PDT- and CDT-induced mechanism of antibacterial action for the material, showing the ZnO core coated with ONP-loaded ZIF-8 MOFs. Upon being exposed to ONOO, MB would be generated from ONP, hence exhibiting fluorescence. MB generation can be used as a marker for infection sites for detection, as a result of the over expression of ONOO and low pH at infection sites. When irradiated, the nanoparticles exhibit antibacterial properties as a result of ROS generation. Reproduced with permission from [110].