Table 4.
Association results between the verbal memory scores and hippocampal subfield volumes in TREND-0 (n = 1806).
| Volume | Short-Term Retrieval | Long-Term Retrieval | Long-Term Retrieval (Young) | Long-Term Retrieval (Old) |
|---|---|---|---|---|
| Whole HC | 0.550 (+) | 0.100 (+) | 0.740 (− | 0.017 (+) |
| CA1 | 0.930 (+) | 0.160 (+) | 0.540 (−) | 0.015 (+) |
| CA3 | 0.320 (+) | 0.210 (+) | 0.940 (+) | 0.120 (+) |
| CA4 | 0.340 (+) | 0.071 (+) | 10.000 (+) | 0.027 (+) |
| Presubiculum | 0.650 (+) | 0.120 (+) | 0.550 (+) | 0.100 (+) |
| Subiculum | 0.620 (+) | 0.170 (+) | 0.400 (−) | 0.018 (+) |
| Parasubiculum | 0.660 (+) | 0.350 (+) | 0.510 (+) | 0.430 (+) |
| Molecular layer DG | 0.690 (+) | 0.080 (+) | 0.710 (+) | 0.009 (+) |
| Granule layer DG | 0.360 (+) | 0.060 (+) | 0.980 (−) | 0.019 (+) |
| HC tail | 0.980 (+) | 0.970 (+) | 0.760 (−) | 0.760 (+) |
| Fimbria | 0.490 (+) | 0.330 (+) | 0.610 (+) | 0.310 (+) |
| Fissure | 0.330 (−) | 0.530 (+) | 0.510 (−) | 0.280 (+) |
| HATA | 0.350 (+) | 0.870 (+) | 0.410 (−) | 0.310 (+) |
The p-values and effect directions (in brackets, positive +, negative −) are presented, significant results are displayed in bold. Analyses were adjusted for age, sex, intracranial volume, educational attainment, and PHQ-9 sum score. HC, hippocampus; CA, cornu ammonis; DG, dentate gyrus; HATA, hippocampus–amygdala transition area. The sample was separated by median split (median = 50 years).