Table 1.
KRAS mutation rate and subtype proportion in common cancers.
| Cancer Type | KRAS Mutation | ||||
|---|---|---|---|---|---|
| N of Samples | Rate (%) | Top 3 Subtypes (Proportion of All KRAS Mutations, %) |
|||
| Pan-cancer | 87,606 | 11.60 | G12D (29.19) | G12V (22.97) | G12C (13.43) |
| Pancreatic adenocarcinoma | 990 | 81.72 | G12D (40.20) | G12V (31.96) | G12R (17.10) |
| Colorectal carcinoma | 3853 | 37.97 | G12D (28.04) | G12V (18.50) | G13D (18.10) |
| Non-small cell lung cancer | 4584 | 21.20 | G12C (45.42) | G12V (15.78) | G12D (13.03) |
Data acquired from cBioPortal.org. G12: codon 12 encoding glycine; G13: codon 13 encoding glycine.