Figure 4.
Mercury intrusion porosimetry (MIP) and compression tests demonstrating effects of calcium carbonate microcapsules on porous structures and mechanical strength of the thermosensitive 1%, 2%, and 5% calcium carbonate microcapsules–2% and 5% (w/v) nanohydroxyapatite–10% (w/v) β-glycerophosphate–4:1 (w/w) chitosan/collagen hydrogel (nHA–CaCO3–chitosan/collagen). MIP analysis on (A) percentages of total porosity and (B) permeability. (C) Compressive strength of the hydrogels. The abbreviation mdracy denotes millidarcy (1 Darcy is approximately 10−12 m2), and ns denotes “not significantly different at p > 0.05”. Symbols *, **, and *** represent significantly different values with p < 0.05, p < 0.01, and p < 0.001, respectively (n = 5, mean ± SD).