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. 2022 Dec 30;13(1):57. doi: 10.3390/metabo13010057

Table 2.

Metabolite information of SMZ in pigs, chickens and rats.

Compound Chemical Name [M+H] (Da) Formula Major Product Ions
S0 4-Amino-N-(5-methyl-3-isoxazolyl) 254.0521 C10H11N3O3S 156, 108, 92, 188, 99, 147
S1 N-Acetyl sulfamethoxazole 296.0627 C12H13N3O4S 198, 134, 188
S2 4-Amino-N-(5-hydroxymethyl-3-isoxazolyl) 270.0564 C10H11N3O4S 252, 204, 156, 147, 108, 92
S3 4-Hydroxyamino-N-(5-methyl-3-isoxazolyl) 270.0564 C10H11N3O4S 204, 172, 108
S4 Sulfamethoxazole-N4-slufate 334.0172 C10H11N3O6S2 254, 156
S5 sulfamethoxazole-
N4-glucuronide
430.0945 C16H19N3O9S 332, 254, 156,
147, 99