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. 2022 Dec 26;16(1):31. doi: 10.3390/ph16010031

Table 2.

CADSS mean score differences over time adjusted by dose (N = 70).

30 min 60 min
Coefficient (CI 95%) p Coefficient (CI 95%) p
Day 1 0.483 0.006
Day 8 0.01 (−2.56–2.58) 0.994 −1.62 (−3.46–0.22) 0.084
Day 15 −1.08 (−4.28–2.11) 0.507 −2.21 (−4.45–0.03) 0.053
Day 22 −1.62 (−5.03–1.80) 0.354 −4.01 (−6.39–−1.63) 0.001 a
Day 29 −2.59 (−6.08–0.89) 0.145 −4.26 (−6.69–−1.84) 0.001 a
Day 36 −2.52 (−6.06–1.02) 0.164 −4.10 (−6.56–−1.63) 0.001 a
Dose 2.29 (−4.40–8.98) 0.502 4.38 (−0.10–8.86) 0.055
Constant 5.74 (1.63–9.85) 0.006 1.65 (−1.04–4.34) 0.230

a Time effect not related to dose.