| AD | Alzheimer Disease |
| ALIX | ALG-2-interacting protein X |
| ALP | Autophagy Lysosomal Pathway |
| APP | Amyloid Precursor Protein |
| ARF6 | ADP-Ribosylation Factor 6 |
| ARRDC1 | Arrestin 1 Domain–Containing Protein 1 |
| Aβ | Amyloid β |
| BACE1 | Beta-Secretase 1 |
| BBB | Blood-Brain Barrier |
| BDNF | Brain Derived Neurotrophic Factor |
| BDNF | Brain-Derived Neurotrophic Factor |
| CCT | Chaperonin containing tailless complex polypeptide |
| CHMP4C | Caveolin-1 and charged MVP Protein 4C |
| circRNAs | Circular RNA |
| CJD | Creutzfeldt-Jakob Disease |
| CNS | Central nervous system |
| CS | Chaperone System |
| CSF | Cerebrospinal Fluid |
| DNAJB1 | DnaJ Heat Shock Protein Family (Hsp40) Member B1 |
| DNAJC5 | DnaJ Heat Shock Protein Family (Hsp40) Member C5 |
| ERK | Extracellular signal-Regulated Kinase |
| ESCRT | Endosomal-Sorting Complex Required for Transport |
| EV | Extracellular vesicle |
| FFI | Fatal Familial Insomnia |
| GDNF | Glial cell line-Derived Neurotrophic Factor |
| GPI | Glycosylphosphatidylinositol |
| GSLs | Glycosphingolipids |
| GSS | Gerstmann–Sträussler–Scheinker disease |
| HD | Huntington Disease |
| Hsc70 | Heat shock cognate 71 kDa protein |
| hsiRNAs | hydrophobically modified siRNAs |
| Hsp | Heat shock protein |
| HSPA4 | Heat Shock Protein Family A (Hsp70) Member 4 |
| HSPBs | small Heat Shock Proteins family |
| HTT | huntingtin gene |
| IGF1R | Insulin-like Growth Factor1 Receptor |
| IL-1β | Interleukin 1β |
| IL-6 | Interleukin 6 |
| IL-8 | Interleukin 8 |
| ILVs | Intraluminal vesicles |
| LAMP2 | Lysosome-Associated Membrane Protein 2 |
| LB | Lewy Bodies |
| lncRNAs | long non-coding RNAs |
| MHC | Major Histocompatibility Complex |
| MLCK | Myosin Light Chain Kinase |
| MMPs | Matrix Metalloproteinases |
| MVBs | Multivesicular Bodies |
| MVs | Microvesicles |
| NDE | Neural Derived Exosomes |
| NDEVs | Neural-Derived Evs |
| nSMase2 | neutral Sphingomyelinase 2 |
| PARK9/ATP13A2 | P-type ATPase ion pump |
| PD | Parkinson Disease |
| PDCD6IP | Programmed Cell Death 6 Interacting Protein |
| PLD | Phospholipase D |
| PM | Plasma Membrane |
| poly Q | polyglutamine |
| PQC | Protein Quality Control |
| PrPC | prion protein |
| REST | repressor element 1-silencing transcription factor |
| RVG | Rabies Virus Glycoprotein |
| SASP | Senescence-Associated Secretory Phenotype |
| sHsps | small Hsps |
| SIMPLE | Small Integral Membrane Protein of the Lysosome/late Endosome |
| SNARE | Transmembrane protein complex soluble N–ethylmaleiamide-Sensitive factor Attachment protein Receptor |
| TSAP6 | Tumor Suppressor-Activated Pathway 6 |
| UPS | Ubiquitin-Proteasome System |
| VPS4 | Vacuolar Protein Sorting-associated protein 4 |
| vSNARE | vesiclular SNARE |
| VTA1 | Vesicle Trafficking 1 |