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. 2022 Dec 29;15(1):123. doi: 10.3390/pharmaceutics15010123

Table 1.

Independent parameters and their corresponding levels in the BBD for the optimization process.

Independent Parameters Symbol Corresponding Levels
Low Level (−1) Center Level (0) High Level (+1)
Shellac concentration (% w/w) x1 36 38 40
Solution feed rate (mL/h) x2 0.4 0.8 1.2
Electrical voltage (kV) x3 12 18 24
KP extract content (% w/w) x4 1 3 5