Table 1.

Ongoing clinical trials of SGLT2 targeting BC.

	Title	Status	Study Results	Conditions	Interventions	Phases	NCT Number
1	Alpelisib, Fulvestrant and Dapagliflozin for the Treatment of HR+, HER2-, PIK3CA Mutant Metastatic Breast Cancer	Recruiting	No Results Available	Metastatic BC HER2-negative BC	Dapagliflozin 10 Mg Tab	Phase 2	NCT05025735
2	A Phase 1b/2 Study of Serabelisib in Combination with Canagliflozin in Patients with Advanced Solid Tumors	Unknown status	No Results Available	BC Endometrial Cancer Lung Cancer Colorectal Cancer Head and Neck Cancer	Serabelisib Canagliflozin 300 mg	Phase 1 Phase 2	NCT04073680
3	Preventing High Blood Sugar in People Being Treated for Metastatic Breast Cancer	Recruiting	No Results Available	BC BC Stage IV Metastatic BC	Dietary Supplement: Ketogenic Diet Dietary Supplement: Low Carbohydrate Diet Drug: Alpelisib Drug: Fulvestrant Drug: Canagliflozin	Phase 2	NCT05090358
4	Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment with Alpelisib and Fulvestrant	Recruiting	No Results Available	BC	Alpelisib Fulvestrant Metformin XR Dapagliflozin + metformin XR Dapagliflozin	Phase 2	NCT04899349