Table 2.
Identification results by PMF of the statistically relevant spots, detected by proteomic analysis on BALF samples. Spot number, corresponding to that in Figure 1 and Figure 2, UniProt protein name, entry name and accession number, MetaCore name, pI and MW and Mascot search results such as score, matched peptides, and coverage % were reported.
| Mascot Search Results | ||||||||
|---|---|---|---|---|---|---|---|---|
| Spot n° | Protein Name | Entry Name | Accession Number |
MetaCore Name | pI MW | Score | Matched Peptides | Coverage (%) |
| 3 | Immunoglobulin heavy constant alpha 1 Fragment N | IGHA1_HUMAN | P01876 | IGHA1, IgA, IgA1 | 6.08–38,486 | 184 | 14/18 | 28 |
| 5 | Ferritin light chain | FRIL_HUMAN | P02792 | FTL | 5.51–20,064 | 187 | 18/47 | 68 |
| 7 | Hemoglobin subunit alpha | HBA_HUMAN | P69905 | Alpha1-globin | 8.72–15,305 | 181 | 10/12 | 69 |
| 10 | Retinol-binding protein 4 | RET4_HUMAN | P02753 | RBP4 | 5.76–23,337 | 136 | 8/14 | 52 |
| 13 | Immunoglobulin heavy constant alpha 1 Fragment N | IGHA1_HUMAN | P01876 | IGHA1, IgA, IgA1 | 6.08–38,486 | 163 | 11/13 | 25 |
| 14 | Haptoglobin | HPT_HUMAN | P00738 | HP, HP-alpha, HP-beta | 6.13–45,861 | 123 | 9/17 | 20 |
| 15 | Hemoglobin subunit beta | HBB_HUMAN | P68871 | VV-Hemorphin-7 | 6.75–16,102 | 138 | 8/10 | 61 |
| 16 | Hemoglobin subunit alpha | HBA_HUMAN | P69905 | Alpha1-globin | 8.72–15,305 | 135 | 7/7 | 61 |
| 17 | Beta-2-microglobulin | B2MG_HUMAN | P61769 | Beta-2-microglobulin | 6.06–13,820 | 250 | 11/11 | 87 |
| 19 | Fatty acid-binding protein, adipocyte | FABP4_HUMAN | P15090 | Fatty acid-binding protein | 6.59–14,824 | 207 | 13/18 | 68 |
| 22 | Beta-2-microglobulin | B2MG_HUMAN | P61769 | Beta-2-microglobulin | 6.06–13,820 | 84 | 4/5 | 44 |
| 25 | Annexin A3 | ANXA3_HUMAN | P12429 | Annexin III | 5.63–36,524 | 86 | 6/6 | 17 |
| 28 | Hemoglobin subunit alpha Fragment N | HBA_HUMAN | P69905 | Alpha1-globin | 8.72–15,305 | 81 | 5/6 | 34 |
| 29 | Protein S100-A9 | S10A9_HUMAN | P06702 | Calgranulin B | 5.71–13,291 | 151 | 7/9 | 84 |
| 30 | Protein S100-A6 | S10A6_HUMAN | P06703 | Calcyclin | 5.33–10,230 | 111 | 10/13 | 40 |
| 31 | Albumin fragment C | ALBU_HUMAN | P02768 | Albumin | 5.92–71,317 | 135 | 11/18 | 18 |
| 32 | Immunoglobulin kappa constant | IGKC_HUMAN | P01834 | IGKC | 6.11–11,929 | 132 | 6/7 | 59 |
| 33 | Rho GDP-dissociation inhibitor 1 | GDIR1_HUMAN | P52565 | RhoGDI alpha | 5.01–23,207 | 109 | 7/12 | 31 |
| 34 | Apolipoprotein A-I | APOA1_HUMAN | P02647 | HDL, Apoa1 | 5.56–30,759 | 268 | 20/28 | 53 |
| 35 | Immunoglobulin kappa constant | IGKC_HUMAN | P01834 | IGKC | 6.11–11,929 | 101 | 5/8 | 53 |
| 36 | Alpha-2-HS-glycoprotein | FETUA_HUMAN | P02765 | Fetuin-A, AHSG-A, AHSG-B | 5.43–40,114 | 168 | 16/32 | 40 |
| 37 | Transthyretin | TTHY_HUMAN | P02766 | Transthyretin | 5.52–15,991 | 130 | 7/13 | 72 |
| 38 | Transthyretin | TTHY_HUMAN | P02766 | Transthyretin | 5.52–15,991 | 131 | 7/13 | 57 |
| 40 | Transthyretin | TTHY_HUMAN | P02766 | Transthyretin | 5.52–15,991 | 147 | 7/9 | 64 |
| 42 | Apolipoprotein A-I | APOA1_HUMAN | P02647 | HDL, Apoa1 | 5.56–30,759 | 174 | 13/21 | 37 |
| 43 | Protein S100-A11 | S10AB_HUMAN | P31949 | S100 | 6.56–11,847 | 138 | 8/9 | 58 |
| 46 | Haptoglobin | HPT_HUMAN | P00738 | HP, HP-alpha, HP-beta | 6.13–45,861 | 149 | 9/11 | 24 |
| 53 | Peroxiredoxin-1 | PRDX1_HUMAN | Q06830 | Peroxiredoxin | 8.25–223,225 | 286 | 16/18 | 62 |
| 55 | Immunoglobulin heavy constant gamma | IGHG1_HUMAN | P01857 | IGHG1, IgG, IgG1 | 8.46–36,596 | 130 | 8/11 | 37 |
| 57 | Albumin Fragment C | ALBU_HUMAN | P02768 | Albumin | 5.92–71,317 | 129 | 11/13 | 19 |
| 60 | Immunoglobulin kappa constant | IGKC_HUMAN | P01834 | IGKC | 6.11–11,929 | 76 | 4/9 | 48 |
| 61 | Immunoglobulin kappa constant | IGKC_HUMAN | P01835 | IGKC | 6.11–11,929 | 137 | 7/12 | 78 |
| 63 | Profilin-1 | PROF1_HUMAN | P07737 | Profilin | 8.44–15,216 | 261 | 17/19 | 75 |
| 65 | Cystatin | CYTB_HUMAN | P04080 | Cystatin B | 6.96–11,190 | 93 | 5/10 | 58 |
| 67 | Haptoglobin | HPT_HUMAN | P00738 | HP, HP-alpha, HP-beta | 6.13–45,861 | 232 | 18/23 | 34 |
| 68 | Apolipoprotein A-I | APOA1_HUMAN | P02647 | HDL, Apoa1 | 5.56–30,759 | 248 | 19/28 | 49 |
| 69 | MIX: Pulmonary surfactant-associated protein A2 | SFPA2_HUMAN | Q8IWL1 | SP-A2 | 5.07–26,622 | 146 | 10/22 | 45 |
| Pulmonary surfactant-associated protein A1 | SFTA1_HUMAN | Q8IWL2 | SP-A | 5.07–26,623 | 146 | 10/22 | 45 | |
| Transthyretin | TTHY_HUMAN | P02766 | Transthyretin | 5.52–15,991 | 90 | 6/22 | 71 | |
| 72 | Complement factor B | CFAB_HUMAN | P00751 | Factor B, Factor Ba, Factor Bb | 6.67–86,847 | 273 | 21/25 | 30 |
| 73 | Alpha-2-HS-glycoprotein | FETUA_HUMAN | P02765 | Fetuin-A, AHSG-A, AHSG-B | 5.43–40,114 | 94 | 7/13 | 19 |
| 74 | Calcyphosin | CAYP1_HUMAN | Q13938 | CAPS, Calcyphosin | 6.90–23,650 | 346 | 22/26 | 53 |
| 76 | Immunoglobulin kappa constant | IGKC_HUMAN | P01834 | 6.11–11,929 | 98 | 5/9 | 55 | |
| 77 | Leukocyte elastase inhibitor | ILEU_HUMAN | P30740 | SERPINB1 | 5.90–42,829 | 76 | 5/7 | 15 |
| 78 | Serotransferrin | TRFE_HUMAN | P02787 | Holotransferrin | 6.81–79,294 | 506 | 42/53 | 49 |
| 82 | Immunoglobulin kappa constant | IGKC_HUMAN | P01834 | IGKC | 6.11–11,929 | 118 | 6/10 | 59 |
| 86 | Apolipoprotein A-I | APOA1_HUMAN | P02647 | HDL, Apoa1 | 5.56–30,759 | 175 | 12/16 | 28 |
| 87 | Immunoglobulin heavy constant gamma | IGHG1_HUMAN | P01857 | IGHG1, IgG, IgG1 | 8.46–36,596 | 94 | 6/9 | 27 |