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5-HT receptor groups and subtypes. All 5-HT receptors are G-protein coupled receptors with the exception of the 5-HT3 receptor, which is a ligand-gated channel. Serotonin binds to the 5-HT receptors outside of the cell triggering effector events via various G-protein-triggered signaling pathways. Abbreviations: 5-HT—5-hydroxytryptamine and cAMP—cyclic adenosine monophosphate. Created with BioRender.com.
