Table 4.
Antiaging activities of the Cystoseira abies-marina extracts.
| Sample | Elastase | Tyrosinase | Collagenase | ||
|---|---|---|---|---|---|
| % Inhibition * | IC50 µg/mL | % Inhibition * | IC50 µg/mL | % Inhibition * | |
| UAE-1 | 92.1 ± 0.02 | 45.4 ± 0.14 a | 90.1 ± 0.11 | 7.5 ± 0.43 a | 49.8 ± 0.12 |
| UAE-2 | 23.2 ± 0.19 | >250 b | 52.5 ± 0.58 | 241.6 ± 0.14 b | 0 |
| UAE-3 | 92.1 ± 0.95 | 65.1 ± 0.41 c | 68.0 ± 0.82 | 143.5 ± 0.91 c | 0 |
| UAE-4 | 56.9 ± 0.37 | 231.6 ± 0.12 d | 65.6 ± 0.75 | 156.8 ± 0.48 d | 0 |
| UAE-5 | 62.8 ± 0.71 | 184.6 ± 0.43 e | 0 | >250 e | 33.3 ± 0.77 |
| UAE-6 | 0 | >250 b | 73.1 ± 0.88 | 99.8 ± 0.65 f | 36.7 ± 0.14 |
| UAE-7 | 0 | >250 b | 60.0 ± 1.49 | 185.1 ± 0.69 g | 21.7 ± 0.23 |
| UAE-8 | 68.6 ± 0.28 | 178.8 ± 0.85 f | 85.5 ± 0.62 | 23.4 ± 0.21 h | 12.5 ± 0.66 |
| UAE-9 | 0 | >250 b | 0 | >250 e | 0 |
| UAE-10 | 0 | >250 b | 68.2 ± 0.14 | 140.1 ± 0.11 i | 11.9 ± 0.64 |
| UAE-11 | 60.3 ± 0.52 | 186.5 ± 0.99 g | 80.2 ± 1.6 | 29.7 ± 0.98 j | 0 |
| UAE-12 | 0 | >250 b | 73.5 ± 0.36 | 101.2 ± 0.44 k | 16.2 ± 0.91 |
| MAE-1 | 40.5 ± 0.31 | >250 b | 47.4 ± 0.23 | >250 e | 7.9 ± 0.35 |
| MAE-2 | 56.6 ± 1.23 | 220.8 ± 0.87 h | 65.9 ± 0.73 | 179.8 ± 0.31 l | 22.3 ± 0.69 |
| MAE-3 | 37.9 ± 0.52 | >250 b | 49.4 ± 0.57 | >250 e | 11.2 ± 0.99 |
| MAE-4 | 45.7 ± 0.68 | >250 b | 67.8 ± 0.20 | 175.6 ± 0.47 m | 27.3 ± 0.87 |
| MAE-5 | 39.2 ± 1.99 | >250 b | 0 | >250 e | 9.5 ± 0.26 |
| MAE-6 | 41.8 ± 1.20 | >250 b | 0 | >250 e | 26.9 ± 0.37 |
| MAE-7 | 33.3 ± 0.48 | >250 b | 0 | >250 e | 21.8 ± 0.84 |
| MAE-8 | 28.1 ± 0.56 | >250 b | 0 | >250 e | 5.6 ± 0.64 |
| MAE-9 | 44.7 ± 0.96 | >250 b | 93.2 ± 0.72 | 42.6 ± 0.80 n | 16.0 ± 0.24 |
| MAE-10 | 26.8 ± 0.40 | >250 b | 88.2 ± 0.15 | 65.4 ± 0.33 o | 21.2 ± 0.56 |
| MAE-11 | 19.7 ± 0.51 | >250 b | 30.2 ± 0.81 | >250 e | 13.8 ± 0.56 |
| MAE-12 | 40.0 ± 0.22 | >250 b | 44.1 ± 51 | >250 e | 15.1 ± 0.24 |
| NMAAK ** | 95.5 ± 3.96 | 0.13 ± 0.002 i | - | - | - |
| Kojic Acid | - | - | 99.2 ± 0.36 | 1.82 ± 0.13 p | - |
| EDTA | - | - | - | - | 96.3 ± 1.2 |
* % inhibitory activity at 250 µg/mL; ** N-Methoxysucinil-Ala-Ala-Pro-Val-chloromethylketone; In each column, different letters indicate significant differences (p < 0.05).