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. 2023 Jan 13;15(1):219. doi: 10.3390/v15010219

Figure 2.

Figure 2

Experimental scheme and percent survival of guinea pigs in 42 days (a) Experimental scheme. Guinea pigs were challenged at day 0 and immunized with recombinant adenovirus vaccines, FI-HSV-2, or PBS twice at 1- and 28 dpi. Sera samples were collected at 0, 14, 28, and 42 dpi, and vaginal secretions were collected every alternate day from 0 to 56 dpi. (b) The X-axis shows days post-immunization, and Y-axis shows the percentage of surviving guinea pigs (n = 6 per group). The number to the right is the number of dead animals/total number of animals in each group. Both rAd-gD2ΔUL25 and rAd-gD2 + rAd-ΔUL25 had a survival percentage of 83.3%, rAd-gD2 had 50%, FI-HSV2 and acyclovir had 33.33%, and PBS had 0%.