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. 2023 Jan 9;28(2):677. doi: 10.3390/molecules28020677

Figure 2.

Figure 2

IL-6-signaling complex formation and signal transduction. MDL-A inhibits hexamer formation via binding to gp130-D1 (docking mode and structure shown on right). Signaling complex created from PDBID: 1P9M [25,48]. Docking mode recreated using AutoDock 4.2 [49] and visualized through Chimera [50].