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MTT Assay Data (72 h) and logP Values for N-Unsubstituted Triazole Analogues.
| Compound | SUM159 IC50 (µM) | MDA-MB-231 IC50 (µM) | logP |
|---|---|---|---|
| LS-T-2 | 25.5 ± 2.3 | Inactive | 3.25 |
| LS-T-3 | 55.5 ± 6.4 | Inactive | 3.25 |
| LS-T-4 | 12.4 ± 0.8 | 13 ± 1.4 | 3.25 |
Inactive compounds displayed no activity up to the highest tested concentration of 50 µM. IC50 ± SE. logP values calculated using ChemDraw 18.1.
