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. 2023 Jan 12;24(2):1506. doi: 10.3390/ijms24021506

Figure 4.

Figure 4

Biomarker molecules for use in the diagnostic process of lung cancer (based on [313,314,315,316,317,318,319,320,321,322,323,324,325,326,327,328,329,330,331,332,333,334,335,336]). Abbreviations: p53—tumor protein P53; CAGE—cancer-associated gene protein; NY-ESO-1—New York esophageal squamous cell carcinoma-1; SOX2—SRY-box transcription factor 2; MAGEA4—melanoma-associated antigen 4; HuD—ELAV-like protein 4; PGP 9.5—protein gene product 9.5; GAGE7—G antigen 7; MAGEA1—melanoma-associated antigen 1; IMPDH1—inosine monophosphate dehydrogenase 1; PGAM—phosphoglycerate mutase; HSP-9B—heat shock protein family A member 9B; SEC15L2—EXOC1 exocyst complex component 1; XRCC5—X-ray repair cross complementing 5; MALAT1—metastasis-related lung adenocarcinoma transcript 1; HCC1—nuclear protein Hcc-1; BARD1—BRCA1-associated RING domain protein 1; ECH1—Enoyl-CoA hydratase 1; HNRNPA2B1—heterogeneous nuclear ribonucleoprotein A2/B1; ANXA1—annexin A1; FOXP3—forkhead box protein P3; c-MYC—MYC proto-oncogene; MDM2—mouse double minute 2 homolog; NPM1—nucleophosmin 1; p16—cyclin-dependent kinase inhibitor 2A; TTC14—tetratricopeptide repeat domain 14; BRAF—serine/threonine-protein kinase B-raf; CK8—cytokeratin 8; CK20—cytokeratin 20; CDK2—cyclin-dependent kinase 2; CEA—carcinoembryonic antigen; CYFRA 21-1—cytokeratin 19 fragments; CA 125—cancer antigen 125; CRP—C-reactive protein; HGF—hepatocyte growth factor; ENO1—alpha-enolase; ProGRP—progastrin-releasing peptide; MCP1—monocyte chemoattractant protein 1; IL-6—interleukin-6; IL-10—interleukin-10; NSE—neuron-specific enolase; SAA—serum amyloid A; RBP—retinol-binding proteins; A1AT—alpha-1 antitrypsin; CART—cocaine and amphetamine-regulated transcript; MIP-1α—macrophage inflammatory proteins alpha 1; SCF—Skp, Cullin, F-box-containing complex; TNF RI—tumor necrosis factor receptor I; IFN-γ—interferon gamma; TNF-α—tumor necrosis factor alpha; sIL-6R—soluble interleukin-6 receptor; TTR—transthyretin; THBS1—thrombospondin-1; CCL5—CC motif chemokine ligand 5; MIF—macrophage migration inhibitory factor; PAI-1—plasminogen activator inhibitor 1; ERBB2—erb-b2 receptor tyrosine kinase 2; IGF1—insulin-like growth factor 1; RANTES—regulated upon activation, normal T-cell expressed and secreted; AFP—alpha fetoprotein; MMP-1—matrix metallopeptidase 1; MMP-9—matrix metallopeptidase 9; YKL-40—chitinase-3-like protein; IL-1Ra—interleukin 1 receptor antagonist; sIL-2Ra—human soluble interleukin 2 receptor alpha; SDF-1α+β—stromal cell-derived factor 1 alfa + beta.