TABLE 1.
Characterization of serum-expressed genes (seg)
| Classification | Mutant(s) sibling[s] | Similar gene (EMBL accession no.) | Identitya | Ratio of β-galactosidase activityb | Putative function |
|---|---|---|---|---|---|
| Biosynthesis | seg1 (seg21), seg13, seg14, seg25 (seg50), seg45 (seg48) | lysC (AAD36585.1)c | 39 (157/395) | 75 | Lysine biosynthesis, peptidoglycan biosynthesis |
| seg22 (seg30, seg33) | Putative lysC control region (AAD36585.1)c | 39 (157/395) | 77 | Lysine biosynthesis , peptidoglycan biosynthesis | |
| seg24, seg26 | asd (AAC07674.1)d | 49 (164/333) | 70 | Lysine biosynthesis, peptidoglycan biosynthesis | |
| seg10 | dapA (AAB98232.1)e | 41 (119/285) | 80 | Lysine biosynthesis, peptidoglycan biosynthesis | |
| seg8 | yjcI (CAB13044.1)f | 47 (174/365) | 45 | Methionine biosynthesis | |
| seg29, seg43 | gltA (CAB13728.1)f | 52 (792/1513) | 105 | Glutamate synthesis | |
| Surface protein | seg7 | sai-1 (BAA97049.1)g | 91 (268/293) | 50 | 29-kDa cell surface protein |
| seg37 (seg39, seg40) | sitC (CAA67571.1)h | 76 (235/309) | 68 | Lipoprotein, putative adhesin | |
| Antimicrobial peptide | seg35 | gdhM (AAB61135.1)i | 51 (23/45) | 7 | Lantibiotic gallidermin precursor |
| No database match | seg5 | ? | No significant homologyj | 58 | Unknown |
a
Percentage (number of identical amino acids).
b
Expressed as the ratio of β-galactosidase activity of stationary-phase bacteria cultured in serum versus BHI.
c
Thermotoga maritima.
d
Aquifex aeolicus.
e
Methanococcus jannaschii.
f
B. subtilis.
g
S. aureus.
h
Staphylococcus epidermidis.
i
Staphylococcus gallinarum.
j
Identity score with no significant database match.