Table 2.

Summary of digital health intervention outcomes.

Types of digital health interventions	Studies with positive outcomes	Studies with positive outcomes outnumbered studies with no effect or negative outcomes	Effectiveness of digital health interventions was subject to their type and function	Studies with no effect or negative outcomes outnumbered studies with positive outcomes	Studies with no effect	Studies with negative outcomes
Telemonitoring	N/Aa	Self-manage symptom	Anxiety; depression; distress; fatigue; HRQoLb or QoLc; pain; physical activity; sleep	N/A	N/A	N/A
Telemedicine	N/A	N/A	Anxiety; depression; distress; fatigue; HRQoL or QoL; pain; physical activity; sleep	N/A	N/A	N/A
Wearable	Multipled functions for physical activity	N/A	Anxiety; depression; distress; fatigue; HRQoL or QoL; pain; physical activity; sleep	N/A	N/A	N/A
Web	Inform for anxiety; preventative behavior change for physical activity; self-manage symptoms; treat for cognitive function, depression, fear of cancer recurrence, and sleep; multiple functions for symptom	Inform for decision-making, HRQoL or QoL, and knowledge; self-manage depression, distress, fatigue, and HRQoL or QoL; treat for distress, fatigue, and HRQoL or QoL	Anxiety; depression; distress; fatigue; HRQoL or QoL; pain; physical activity; sleep	Inform for recall of cancer-related information; self-manage intervention for cancer-specific distress and cost; multiple functions for anxiety, breast cancer concerns, and competence (including health care, coping, depression, distress, fatigue, function, functional well-being, HRQoL or QoL, self-efficacy, and social support)	Inform for self-efficacy; self-manage for function, functional well-being, intrusive thoughts, pain, physical activity, and personal control; multiple functions for diet and pain	Communicate for distress
Mobile	N/A	N/A	Anxiety; depression; distress; fatigue; HRQoL or QoL; pain; physical activity; sleep	Self-manage for HRQoL or QoL	N/A	N/A
Web+mobile	Multiple functions for pain	Multiple functions for anxiety and HRQoL or QoL	Anxiety; depression; distress; fatigue; HRQoL or QoL; pain; physical activity; sleep	Multiple functions for depression and sleep	Multiple functions for physical activity	N/A
Telemonitoring+telemedicine	Treat depression and pain	Treat for HRQoL or QoL	Anxiety; depression; distress; fatigue; HRQoL or QoL; pain; physical activity; sleep	N/A	N/A	N/A

^aN/A: not applicable.

^bHRQoL: health-related quality of life.

^cQoL: quality of life.

^dMultiple: multiple digital health functions were combined.