Table 5.
Group | RL, % | SIR | Systemic Alteration | DIC | Distress HPA | |||||
---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | 5 | |||||
Control 1 (donors), n = 50 | 100 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Control 2 (elderly people), n = 22 | 81.8 | 18.2 | 0 | 0 | 0 | 0 | 18.2 1 | 0 | 0 | 0 |
Sepsis non-resuscitative on days 1–2, n = 40 | 0 | 27.5 | 55.0 | 17.5 | 0 | 0 | 100.0 | 5.0 | 10.0 | 0 |
Sepsis on days 1–2, n = 46 | 0 | 4.4 | 10.9 | 41.3 | 30.4 | 13.0 | 100.0 | 34.8 | 58.7 | 30.4 |
Sepsis on days 5–7, n = 13 | 0 | 0 | 7.7 | 46.2 | 46.1 | 0 | 100.0 | 46.2 | 92.3 2,3 | 15.4 |
Septic shock, n = 14 | 0 | 0 | 7.1 | 14.3 | 42.9 | 35.7 | 100.0 | 42.9 | 85.7 | 64.3 |
Tertiary peritonitis, n = 34 | 0 | 0 | 14.7 | 64.7 | 17.7 | 2.9 | 100.0 | 32.4 | 85.3 | 5.9 |
Tertiary peritonitis + SS, n = 17 | 0 | 0 | 35.3 | 58.8 | 5.9 | 0 | 100.0 | 70.8 | 88.2 | 35.3 |
Multiple injuries on days 1–2, n = 51 | 0 | 2.0 | 25.5 | 37.2 | 31.4 | 3.9 | 100.0 | 52.9 | 72.6 | 31.4 |
Multiple injuries on days 5–7, n = 18 | 0 | 5.6 | 44.4 | 22.2 | 27.8 | 0 | 100.0 | 50.0 | 55.6 3 | 50.0 |
Note. RL—reactivity level; SI—systemic inflammation; SIR—systemic inflammatory response; DIC—disseminated intravascular coagulation; HPA—hypothalamic-pituitary-adrenal axis; SS—septic shock. 1—manifestations of SIR in this category of patients can also be associated with chronic low-intensity inflammation connected with age-related changes in homeostasis (allostasis). 2—statistically significant differences in the same nosology group on different days of the study (Chi-square test, p < 0.05); 3—statistically significant differences between the groups “Sepsis 5–7” and “Multiple injuries 5–7” (Chi-square test, p < 0.05).