Table 3.
Patient characteristic | LLA 1–3 years post-DFU | P value | LLA ≥3 years post-DFU | P value |
---|---|---|---|---|
HCC score | 0.97 (0.96–0.98) | <0.0001 | 0.89 (0.88–0.90) | <0.0001 |
Age | 0.98 (0.98–0.98) | <0.0001 | 0.98 (0.97–0.98) | <0.0001 |
National ADI (weighted) | 1.00 (1.00–1.00) | 0.012 | 1.00 (1.00–1.00) | <0.0001 |
Sex (ref = male) | ||||
Female | 1.07 (1.02–1.11) | 0.0017 | 1.08 (1.03–1.12) | 0.0009 |
Race/ethnicity (ref = Non-Hispanic White) | ||||
Black/AA | 0.74 (0.71–0.78) | 0.001 | 0.69 (0.65–0.72) | 0.01 |
Asian | 0.77 (0.66–0.91) | 0.38 | 0.69 (0.58–0.84) | 0.34 |
Hispanic | 0.78 (0.71–0.86) | 0.28 | 0.73 (0.65–0.81) | 0.50 |
Native American | 0.72 (0.59–0.88) | 0.13 | 0.57 (0.45–0.72) | 0.0082 |
Other | 0.90 (0.79–1.03) | 0.14 | 0.84 (0.73–0.98) | 0.11 |
Unknown | 0.89 (0.71–1.10) | 0.45 | 0.83 (0.66–1.05) | 0.35 |
Comorbidities (ref = none) | ||||
Chronic kidney disease | 0.94 (0.87–1.00) | 0.06 | 0.58 (0.54–0.61) | <0.0001 |
Peripheral vascular disease | 0.53 (0.49–0.58) | <0.0001 | 0.30 (0.28–0.33) | <0.0001 |
Stroke/TIA | 1.13 (1.09–1.18) | <0.0001 | 1.14 (1.09–1.20) | <0.0001 |
Heart disease | 0.92 (0.86–0.98) | 0.016 | 0.85 (0.79–0.91) | <0.0001 |
Acute myocardial infarction | 1.11 (1.06–1.17) | <0.0001 | 1.08 (1.02–1.14) | 0.012 |
Data are presented as the OR (95% CI). Reference is to those who received an LLA within 1 year of the index DFU.