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RBD interactions of human coronaviruses with their human protein receptor. The structures of protein–protein interaction of human coronaviruses to the human receptor is presented. At the top from left to right the RBD of HCoV-229E ((A), PDB: 6ATK) with ANPEP and the RBD of MERS-CoV ((B), PDB: 4KR0) with DPP- IV, at the bottom the RBD of SARS2-S ((C), PDB: 6M0J), SARS-S ((D), PDB: 2AJF) and HCoV-NL63 ((E), PDB: 3KBH) interacting with ACE2.
