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. 2023 Jan 9;15(2):332. doi: 10.3390/nu15020332

Figure 4.

Figure 4

Microbiota beta diversity was not affected by increasing protein intake. (A,B): Principle coordinate analysis (PCoA) based on Bray–Curtis dissimilarity (A) and weighted UniFrac (B) measures. These are measures used to evaluate overall microbial compositional differences between groups. Each point indicates one sample from one participant (yellow: diet group, purple: control group, dot: baseline visit (V1), triangle: 6 month follow-up visit (V2)). Points from one participant are linked. The closer the points are mapped together, the more the microbial composition is alike. PERMANOVA analysis showed that overall microbiota composition based on the Bray–Curtis dissimilarity measure or on weighted UniFrac did not change significantly from baseline to follow-up in the intervention compared to the control group. (C,D): Multilevel principal component analysis (PCA) stratified for baseline (V1) and 6 month follow-up visits (V2) (C) and for all visits combined (D). There was no significant (p = 0.43) effect of the dietary intervention on this beta-diversity measure.