TABLE 2.
Unadjusted Association Between Baseline Characteristics and Isolation of P. aeruginosa Isolates with Any gyrA or parC Mutations
| Risk Factor | Isolates with Mutations (N = 172) | Control Group (N = 4,564) | OR (95% CI) | P Value |
|---|---|---|---|---|
| Mean age, y (SD) | 62.3 (15.3) | 54.0 (19.4) | 1.02 (1.02–1.03) | <.001 |
| Male sex, no. (%) | 93 (54.1) | 2,006 (44.0) | 1.50 (1.11–2.04) | .009 |
| Race, no. (%) | ||||
| Black/African-American | 56 (32.6) | 1,901 (41.6) | 0.68 (0.49–0.94) | .02 |
| White | 103 (60.0) | 2,404 (52.7) | ||
| Other | 13 (7.6) | 259 (5.7) | ||
| Hospital, no. (%) | ||||
| PPMC | 45 (26.2) | 1,246 (27.3) | 1.00 (reference) | Reference |
| HUP | 127 (73.8) | 3,318 (72.7) | 1.06 (0.75–1.50) | .74 |
| Mean Elixhauser comorbidity index score (SD) | 3.74 (4.41) | 0.84 (3.04) | 1.18 (1.14–1.21) | <.001 |
| APR-DRG severity of illness score subgroup, no. (%) | 6.91 (5.39–8.85) | <.001 | ||
| Mild | 1 (0.6) | 1,314 (28.8) | ||
| Moderate | 12 (7.0) | 1,702 (37.3) | ||
| Major | 42 (24.4) | 1,135 (24.9) | ||
| Extreme | 117 (68.0) | 411 (9.0) | ||
| Mean time at risk (SD) | 19.1 (34.4) | 5.7 (6.4) | 1.08 (1.06, 1.09) | <.001 |
note. OR, odds ratio; CI: 95% confidence interval; SD, standard deviation; HUP, Hospital of the University of Pennsylvania; PPMC, Penn Presbyterian Medical Center; APR-DRG, All Patient Refined Diagnosis Related Groups.