TABLE 6.
Comparison of Multivariable Models of Risk Factors for Isolation of P. aeuruginosa with gyrA and parC Mutations Versus Isolation of P. aeuruginosa Without gyrA and parC Mutationsa
| Variable | P. aeruginosa with Any gyrA/ParC Mutations Adjusted OR (95% CI) | P Value | P. aeruginosa Without gyrA/ParC Mutations Adjusted OR (95% CI) | P Value |
|---|---|---|---|---|
| Fluoroquinolones | 0.90 (0.81–1.00) | .05 | 0.96 (0.86–1.06) | .39 |
| Time at risk | 0.98 (0.96–1.00) | .46 | 0.96 (0.94–0.99) | .01 |
| Elixhauser comorbidity index score | 1.07 (1.03–1.11) | <.001 | 1.07 (1.02–1.11) | .002 |
| Illness severity | 6.10 (4.65–8.00) | <.001 | 6.19 (4.51–8.49) | <.001 |
| Vancomycin | 1.09 (1.04–1.13) | <.001 | 1.09 (1.03–1.14) | .001 |
| Other agents with extended Gram-positive activity | 1.14 (1.03–1.26) | .01 | 1.13 (1.01–1.25) | .03 |
note. OR, odds ratio; CI, confidence interval.
a
Both case groups were independently compared to control group without isolate.