Table 4.
Comparison of the differences in hematological indices among disease activity subgroups based on composite indices.
| Hematological Indices | Disease Activity Subgroups Based on Composite Indices | |||
|---|---|---|---|---|
| Remission | Low | Moderate to High | p Value | |
| DAS28-ESR | ||||
| SII | 391.2 (265.4–571.6) | 543.5 (366.8–801.9) | 606.5 (423.5–961.3) | <0.001 |
| NHL score | 0.143 (0.102–0.197) | 0.188 (0.112–0.238) | 0.192 (0.127–0.276) | 0.004 |
| NLR | 1.771 (1.302–2.545) | 2.186 (1.460–3.234) | 2.305 (1.618–3.214) | 0.021 |
| PLR | 124.6 (102.7–156.1) | 146.7 (110.4–185.7) | 148.4 (119.8–185.9) | 0.021 |
| DAS28-CRP | ||||
| SII | 440.0 (324.6–733.7) | 598.5 (371.7–750.2) | 672.5 (423.3–1068.4) | 0.001 |
| NHL score | 0.150 (0.102–0.225) | 0.176 (0.119–0.230) | 0.204 (0.131–0.284) | 0.005 |
| NLR | 1.828 (1.314–2.696) | 2.137 (1.485–2.901) | 2.531 (1.699–3.322) | 0.012 |
| PLR | 129.5 (103.1–162.5) | 144.4 (116.9–183.6) | 147.2 (118.7–186.3) | 0.165 |
| SDAI | ||||
| SII | 812.5 (505.8–1266.1) | 507.6 (342.4–762.4) | 757.2 (473.3–1171.3) | 0.001 |
| NHL score | 0.228 (0.176–0.332) | 0.164 (0.115–0.232) | 0.232 (0.138–0.300) | 0.003 |
| NLR | 2.720 (1.910–3.566) | 2.001 (1.437–2.864) | 2.768 (1.771–3.516) | 0.007 |
| PLR | 148.1 (121.0–185.6) | 137.8 (111.0–173.9) | 149.2 (118.7–193.2) | 0.293 |
| CDAI | ||||
| SII | 433.5 (3.27.1–804.8) | 506.0 (338.1–746.1) | 759.5 (477.5–1174.0) | 0.001 |
| NHL score | 0.160 (0.110–0.267) | 0.162 (0.110–0.223) | 0.232 (0.142–0.303) | 0.002 |
| NLR | 1.944 (1.384–3.455) | 1.954 (1.405–2.727) | 2.775 (1.773–3.553) | 0.003 |
| PLR | 131.4 (107.4–163.5) | 137.3 (108.9–172.4) | 149.9 (119.0–196.0) | 0.314 |
p values were calculated by Kruskal–Wallis test. Data are described as median (interquartile range). Abbreviation: DAS, disease activity score; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; VAS, visual analogue scale; CDAI, clinical disease activity index; SDAI, simplified disease activity index; SII, systemic immune-inflammation index; NHL, neutrophil-to-hemoglobin and lymphocyte; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.