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. 2023 Jan 5;11(1):131. doi: 10.3390/vaccines11010131

Table 2.

ADME/T properties of all three compounds select after HTVS.

Ranges
Sr. No.
QPlogPo/w
(−2.0–6.5)
QPlogBB
(−3.0–1.2)
Mol MW
(130.0–725)
Percent Human-Oral Absorption
(>80% Is High <25% Is Poor)
FISA
(7.0–330)
PISA
(0.0–450)
QPlogHERG
(Concern below −5)
QPlogS
(−6.5–0.5)
Comp 1 2.307 0.158 342.827 90.439 115.470 242.988 −3.454 −2.855
Comp 2 0.681 −2.206 343.359 58.803 257.159 304.534 −5.85 −3.726
Comp 3 0.288 −1.553 303.323 69.379 181.286 166.144 −4.592 −2.086