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. 2023 Jan 4;24(2):916. doi: 10.3390/ijms24020916

Table 1.

Demographic characteristics of RRMS patients and their pharmacological treatments.

Characteristic Mild-Moderate Disability
EDSS 0–3 (n = 50)
Severe Disability
EDSS 3.5–7 (n = 25)
p-Value
Female 33 (66%) 17 (68%) NS
Male 17 (34%) 8 (32%) NS
Age 37.7 ± 11.4 43.0 ± 11.1 NS
Years since diagnosis 7.78 ± 5.12 10.2 ± 6.99
EDSS ‡ 1.91 ± 0.88 4.9 ± 1.11 * 0.00001
Progression rate 0.51 ± 0.63 0.99 ± 1.09 * 0.00145
Treatment:
Glatiramer Acetate 19 (38%) 9 (36%) NS
Rituximab 4 (8%) 3 (12%)
Interferon β 14 (28%) 5 (2%)
Fingolimod 5 (10%) 2 (8%)
Azathioprine 0 3 (12%)
Natalizumab 1 (2%) 1 (4%)
Dimethyl fumarate 3 (6%) 1 (4%)
None 4 (8%) 1 (4%)

‡ EDSS = Expanded Disability Status Scale. Progression rate = EDSS/years with the disease. Comparisons were performed with the t-test, Mann–Whitney test, or χ2, as appropriate. * significant, NS (Not Significant).