Skip to main content
. 2022 Dec 27;13(1):42. doi: 10.3390/metabo13010042

Figure 5.

Figure 5

Baseline BG and BHB correlate with post-hypoglycemic epinephrine. Plasma epinephrine and glucagon concentrations were measured in animals subjected to a single (1×-Hypo) or recurrent (3×-Hypo) insulin injections; in the 3×-Hypo groups epinephrine and glucagon were measured after the final insulin injection. (A) In non-diabetic keto-fed rats baseline BG inversely correlated with plasma epinephrine, but not glucagon, measured 2 h after insulin injection (n = 12); (B) Direct correlation was detected between baseline BHB and epinephrine in non-diabetic keto-fed rats, and no correlation with glucagon; (C) Baseline BG did not correlate with epinephrine or glucagon in STZ-diabetic keto-fed rats (n = 10); (D) Baseline BHB significantly correlated with glucagon, but not epinephrine in STZ-diabetic keto-fed rats; (E) Baseline BG was not associated with changes in epinephrine or glucagon in non-diabetic chow-fed rats (n = 10) or (F) STZ-diabetic chow-fed rats (n = 9). Concentrations of epinephrine ang glucagon (pg/mL) were log-transformed for analysis. Data analysed by Spearman’s correlation. Datapoints are individual animals.