TABLE 2.
Development of bacteremia and meningitis (defined as positive CSF cultures) in newborn rats receiving E. coli K1 strain E44 (RS 218 Rifr, 018:K1:H7) or its isogenic mutants
| E. coli strain | No. of animals | Bacteremia (log CFU/ml of blood) | No. (%) of animals with positive CSF | Reference(s) |
|---|---|---|---|---|
| E44 | 19 | 7.18 ± 0.63 | 12 (63) | 48 |
| ΔompA | 22 | 7.05 ± 0.49 | 6 (27)a | |
| E44 | 24 | 7.51 ± 1.25 | 16 (67) | 20 |
| ΔibeA | 25 | 6.97 ± 1.21 | 4 (16)a | |
| E44 | 27 | 7.01 ± 1.17 | 15 (56) | 19 |
| ΔibeB | 25 | 7.06 ± 1.29 | 4 (16)a | |
| E44 | 24 | 7.53 ± 0.40 | 18 (75) | 47 |
| ΔibeC | 24 | 7.80 ± 0.67 | 10 (42)a | |
| E44 | 17 | 7.50 ± 0.32 | 14 (82) | 18 |
| ΔaslA | 22 | 7.60 ± 0.49 | 7 (32)a | |
| E44 | 51 | 7.22 ± 0.59 | 34 (6) | 3, 4 |
| ΔtraJ | 50 | 7.10 ± 0.44 | 23 (4)a | |
| E44 | 26 | 6.06 ± 1.49 | 10 (38) | 4, Wang et al.b |
| Δcnf1 | 28 | 6.07 ± 1.21 | 3 (11)a |
a
Significantly less than result for E44.
b
Wang et al., Abstr. 100th Gen. Meet. Am. Soc. Microbiol.