Table 1.
The pathways positively correlated with CHD4 in TCGA were analysed by gene set enrichment analysis
| Signaling name | Size | NES | NOM p-val | FDR q-val | FWER p-val | Rank at max |
|---|---|---|---|---|---|---|
| NOTCH_SIGNALING_PATHWAY | 47 | 2.101641 | 0 | 0.010654 | 0.006 | 11,320 |
| INOSITOL_PHOSPHATE_METABOLISM | 54 | 2.050652 | 0 | 0.016514 | 0.016 | 15,207 |
| BASAL_CELL_CARCINOMA | 55 | 2.034353 | 0 | 0.012997 | 0.018 | 10,713 |
| ADHERENS_JUNCTION | 73 | 2.017389 | 0.002004 | 0.012376 | 0.028 | 9599 |
| PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM | 76 | 1.979099 | 0.001992 | 0.015025 | 0.039 | 15,207 |
| WNT_SIGNALING_PATHWAY | 150 | 1.978311 | 0.002037 | 0.012521 | 0.039 | 12,401 |
| TASTE_TRANSDUCTION | 51 | 1.940397 | 0 | 0.017843 | 0.054 | 16,175 |
| HEDGEHOG_SIGNALING_PATHWAY | 56 | 1.872574 | 0.00404 | 0.039105 | 0.13 | 12,001 |
| LYSINE_DEGRADATION | 44 | 1.855039 | 0.003937 | 0.042479 | 0.154 | 13,292 |
| MELANOGENESIS | 101 | 1.838217 | 0.006 | 0.047405 | 0.184 | 16,175 |
| ERBB_SIGNALING_PATHWAY | 87 | 1.809339 | 0.005882 | 0.057518 | 0.222 | 16,540 |
| COLORECTAL_CANCER | 62 | 1.807526 | 0.008032 | 0.053987 | 0.227 | 10,941 |
| ENDOMETRIAL_CANCER | 52 | 1.803657 | 0.008032 | 0.051899 | 0.231 | 10,941 |
| THYROID_CANCER | 29 | 1.756727 | 0.008163 | 0.076846 | 0.313 | 14,471 |
| PROSTATE_CANCER | 89 | 1.753645 | 0.010225 | 0.0733 | 0.316 | 11,645 |
| GNRH_SIGNALING_PATHWAY | 101 | 1.749633 | 0.006061 | 0.070386 | 0.32 | 16,894 |
| AXON_GUIDANCE | 129 | 1.739887 | 0.014028 | 0.072038 | 0.339 | 16,047 |
| SPLICEOSOME | 127 | 1.727772 | 0.022 | 0.075285 | 0.356 | 6232 |
| UBIQUITIN_MEDIATED_PROTEOLYSIS | 134 | 1.722847 | 0.01222 | 0.074673 | 0.369 | 12,985 |