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. 2023 Jan 16;24(2):1776. doi: 10.3390/ijms24021776

Figure 7.

Figure 7

Effects of FGFR3 gene silencing and FGFR3 kinase inhibition on apoptosis of cultured UTUC cells. (A) BFTC-909 cells were treated with either FGFR3-targeted siRNA, scramble non-target control (NTC), or PD173074 at 10 nM for 48 h and subjected to TUNEL fluorescent staining. The TUNEL-positive apoptotic cells show green fluorescence, while DAPI blue fluorescence indicates nuclei of all cells. Original magnification: 100×. (B) Morphometry analysis on TUNEL-positive rates in the treated cells. Density data are expressed as mean ± SEM (n = 8). *** indicates p < 0.001 vs. control group. ND, not detectable.