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. 2023 Jan 3;15(1):164. doi: 10.3390/pharmaceutics15010164

Table 8.

Skin irritation grading scale and their clinical implications.

Clinical Portrayal Grade
No erythema 0
Slight erythema that is barely perceptible 1
Moderate erythema that is visible 2
Erythema and papules 3
Severe Edema 4
Erythema, edema, and papules 5
Vesicular eruption 6
Strong reaction spreading beyond the application sight 7