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. 2022 Dec 29;13(1):100. doi: 10.3390/life13010100

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of ALS-L1023 on the mRNA expression of anti-angiogenesis and hedgehog signaling pathway markers. (A) mRNA expression of angiogenic factors (VEGF and FGF2) and anti-angiogenic factor (THBS1) in liver tissue. (B) mRNA expression of genes related to the hedgehog signaling pathway. ALS-L1023 was treated with dose of 800 mg/kg/day. Data are presented as mean ± standard deviation and were analyzed by Mann-Whitney U test. * p < 0.05, ** p < 0.01 compared to the choline-deficient high-fat (CDHF) group.