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. 2023 Jan 4;24(2):910. doi: 10.3390/ijms24020910

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Oncoprints of fatty acid (FA) metabolism genes in the cancer genome atlas (TCGA, PanCancer Atlas) PCa patient cohort (PRAD). About 88% of the tumors from 489 patients in PRAD showed altered gene copy number or expression of FA metabolism-related genes. ACLY: ATP citrate lyase; ACACA: acetyl-CoA carboxylase alpha (ACC); FASN: fatty acid synthase; ACCS2: acyl-CoA synthetase short-chain family member 2; MLYCD: malonyl-CoA decarboxylase; SCD: stearoyl-CoA desaturase; SREBF1: sterol regulatory element-binding transcription factor 1 (SPREBP1); CPT1A: carnitine palmitoyltransferase 1A; PPARA: peroxisome proliferator-activated receptor alpha; GPAM: glycerol-3-phosphate acyltransferase; AGPAT: 1-acylglycerol-3-phosphate O-acyltransferase; LPCAT1: lysophosphatidylcholine acyltransferase 1; LPIN1: lipin 1; DGAT1: diacylglycerol O-acyltransferase 1; PNPLA2: patatin-like phospholipase domain containing 2; LIPE: lipase, hormone-sensitive; MGLL: monoglyceride lipase.