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. 2023 Jan 15;13(1):131. doi: 10.3390/metabo13010131

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Metabolites with a significantly different fold change after the OGTT between T2D and control subjects. (a) Volcano plot of the differences in plasma metabolite concentration changes 90 min after 75 g glucose ingestion between patients with T2D and controls. Y-axis shows –log₁₀ false discovery rate. Red dots depict significant results. (b) Zoom-out on the significant metabolites from panel (a). (c) Fold and percentage changes of the significant metabolites after the OGTT for T2D and control subjects. In blue, acylcarnitines; in brown, amino acids; in light blue, acyl ethanolamides; in green, monosaccharides; in magenta, xenobiotics; in orange, free fatty acids.