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. 2023 Jan 15;13(1):131. doi: 10.3390/metabo13010131

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Correlation matrix between plasma concentration change of metabolites that significantly differ in response to the OGTT between controls and T2D individuals (rows) and several clinical parameters (columns). A black dot indicates a statistically significant correlation between the respective metabolite and parameter (p < 0.05). Glc AUC_OGTT: glucose area under the curve during the OGTT. HbA1c, glycosylated hemoglobin. Ins AUC_OGTT: insulin area under the curve during the OGTT. IGI: insulinogenic index. FFA: free fatty acid. In blue, acylcarnitines; in brown, amino acids; in light blue, acyl ethanolamides; in green, monosaccharides; in magenta, xenobiotics; in orange, free fatty acids.