Table 4.

Drugs excluded from the final list for having pKi values lower than five.

Drug	ATC	M1_pKi	M2_pKi	M3_pKi	M4_pKi	M5_pKi	Mu_pKi
Acetylsalicylic acid	N02BA01		<5			<5
Amisulpride	N05AL05	<5	<5	<5	<5	<5
Buproprion	N06AX12	<5	<5	<5	<5	<5
Celecoxib	M01AH01		<5			<5
Desvenlafaxine	N06AX23	<5	<5	<5	<5	<5
Fluvoxamine	N06AB08	<5					<5
Metoclopramide	A03FA01						<5
Molindone	N05AE02	3.55	3.35	<5		<5
Pramipexole	N04BC05	<5	<5	<5	<5	<5
Trazodone	N06AX05	<5	<5	<5	<5	<5
Venlafaxine	N06AX16	<5	<5	<5	<5	<5	4.52
Thiopental	N05CA19			4.12
Cimetidine	A02BA01						4.14
Ranitidine	A02BA02						3.92
Terfenadine	R06AX12						4.92

pK_i—the negative logarithm to base 10 of the K_i. M1—muscarinic receptor M1; M2—muscarinic receptor M2; M3—muscarinic receptor M3; M4—muscarinic receptor M4; M5—muscarinic receptor M5; and Mu—muscarinic acetylcholine receptor (no specific subtype).