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. 2023 Jan 14;14(1):47. doi: 10.3390/jfb14010047

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Cytotoxicity of the silver nanoparticle in plants and animals and its mechanism (a) Accumulation and penetration of AgNPs in different organs including the blood–brain barrier; (b) uptake, translocation, and major phytotoxicity of AgNPs in the plant (image adapted and modified from [205]); and (c) possible cytotoxicity molecular mechanism induced by AgNPs. Autophagosome is strongly linked with the protein corona formation for uptake of AgNPs in the cell (Image adapted and modified from [206]).