Table 4.
Effect of chrysin and BM-MSCs on liver glycogen content, G-6-Pase, and glycogen phosphorylase activities in NA/STZ-induced diabetic rats.
| Groups | Liver Glycogen (mg/g Tissue) |
% Change |
G-6-Pase (mg Pi Liberated/g Tissue/Hour) |
% Change |
Glycogen Phosphorylase (mg Pi Liberated/g Tissue/Hour) |
% Change |
|---|---|---|---|---|---|---|
| Normal | 36.84 ± 1.10 d | 14.89 ± 0.67 a | 11.69 ± 0.50 a | |||
| Diabetic control | 16.76 ± 0.34 a | −52.69 | 28.75 ± 0.67 d | 93.08 | 25.78 ± 0.48 d | 120.53 |
| Diabetic treated with chrysin | 23.54 ± 1.1 b | 40.45 | 18.44 ± 0.73 b | −35.86 | 18.83 ± 0.29 b,c | −26.96 |
| Diabetic treated with BM-MSCs | 21.01 ± 0.25 b | 25.36 | 20.01 ± 0.94 b,c | −30.40 | 16.47 ± 0.88 b | −36.11 |
| Diabetic treated with chrysin and BM-MSCs | 28.19 ± 1.19 c | 68.20 | 21.77 ± 0.63 c | −24.28 | 19.03 ± 0.56 c | −26.18 |
| F-probability | p < 0.001 | p < 0.001 | p < 0.001 | |||
Data are expressed as mean ± SE. Six samples from each group were detected. Means (with various superscript symbols: a, b, c, and d) for each parameter differ significantly at p < 0.05. Percentage changes were calculated by comparing the diabetic control with normal and diabetic treated groups with diabetic control. % change = [(Final − Initial)/Initial] × 100.