Table 1.
Overall properties (hydrodynamic diameter (DH), polydispersity index (PDI), ζ potential, encapsulation efficiency (EE) and actual loading (AL)) of SET-M33-loaded PLGA NPs.
| Formulation | DH
(nm) ± SD |
PDI (mean) ± SD |
ζ potential (mV) ± SD | EE (%) ±SD |
AL (mg SET-M33/100 mg NPs) ± SD |
|---|---|---|---|---|---|
| M33_PEG2000 NPs | 208.8 ± 1.5 | 0.141 ± 0.020 | −18.4 ± 0.7 | 93.9 ± 1.25 | 3.793 ± 0.045 |
| M33_PEG5000 NPs | 185.7 ± 1.8 | 0.09 ± 0.044 | −18.87 ± 0.6 | 85.9 ± 4.63 | 3.557 ± 0.159 |
DH, hydrodynamic diameter; PDI, polydispersity index; EE, encapsulation efficiency, calculated as actual loading/theoretical loading × 100; AL, actual loading.