Table 2.
Univariable and multivariable Cox regression model analyses of OS for nomogram.
| Characteristics | Univariable Analysis | Multivariable Analysis | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p | OR | 95% CI | p | |
| Age | <0.001 | <0.001 | ||||
| ≤50 | Reference | 1 | Reference | 1 | ||
| 51–65 | 1.132 | 0.976–1.312 | 0.101 | 1.143 | 0.984–1.328 | 0.081 |
| >65 | 1.439 | 1.244–1.665 | <0.001 | 1.517 | 1.297–1.774 | <0.001 |
| Gender | 0.642 | |||||
| Female | Reference | 1 | - | |||
| Male | 0.902 | 0.597–1.362 | ||||
| Marital status | <0.001 | <0.001 | ||||
| Mariied | Reference | 1 | Reference | 1 | ||
| Unmarried | 1.327 | 1.192–1.476 | <0.001 | 1.254 | 1.124–1.399 | <0.001 |
| Insurance | 0.21 | |||||
| No | Reference | 1 | - | |||
| Yes | 1.144 | 0.927–1.411 | ||||
| Race | <0.001 | <0.001 | ||||
| White | Reference | 1 | Reference | 1 | ||
| Black | 1.317 | 1.157–1.499 | <0.001 | 1.320 | 1.153–1.511 | <0.001 |
| Other | 0.848 | 0.700–1.029 | 0.095 | 0.838 | 0.690–1.018 | 0.075 |
| Grade | <0.001 | 0.008 | ||||
| I/II | Reference | 1 | Reference | 1 | ||
| III/IV | 1.526 | 1.372–1.696 | <0.001 | 1.480 | 1.311–1.670 | <0.001 |
| T stage | <0.001 | <0.001 | ||||
| T1 | Reference | 1 | Reference | 1 | ||
| T2 | 1.149 | 0.950–1.390 | 0.153 | 1.094 | 0.904–1.325 | 0.355 |
| T3 | 1.343 | 1.093–1.649 | <0.001 | 1.184 | 0.963–1.457 | 0.109 |
| T4 | 1.486 | 1.239–1.782 | <0.001 | 1.301 | 1.083–1.563 | 0.005 |
| N stage | 0.82 | |||||
| N0 | Reference | 1 | - | |||
| N1 | 1.00875743 | 0.884–1.152 | 0.897 | |||
| N2 | 0.951846599 | 0.794–1.141 | 0.593 | |||
| N3 | 1.044337376 | 0.883–1.235 | 0.612 | |||
| Surgery | <0.001 | <0.001 | ||||
| No | Reference | 1 | Reference | 1 | ||
| Yes | 0.711 | 0.635–0.796 | <0.001 | 0.667 | 0.589–0.755 | <0.001 |
| Chemotherapy | <0.001 | <0.001 | ||||
| No | Reference | 1 | Reference | 1 | ||
| Yes | 0.811 | 0.730–0.901 | <0.001 | 0.667 | 0.589–0.755 | <0.001 |
| Radiation | 0.356 | |||||
| No | Reference | 1 | - | |||
| Yes | 0.949 | 0.849–1.061 | 0.356 | |||
| Bone metastatic | 0.006 | <0.001 | ||||
| No | Reference | 1 | Reference | 1 | ||
| Yes | 1.156 | 1.042–1.282 | 0.006 | 1.257 | 1.122–1.409 | <0.001 |
| Brain metastatic | <0.001 | <0.001 | ||||
| No | Reference | 1 | Reference | 1 | ||
| Yes | 1.845 | 1.567–2.171 | <0.001 | 1.753 | 1.482–2.072 | <0.001 |
| Liver metastatic | <0.001 | <0.001 | ||||
| No | Reference | 1 | Reference | 1 | ||
| Yes | 1.707 | 1.527–1.908 | <0.001 | 1.694 | 1.507–1.905 | <0.001 |
| ER | <0.001 | <0.001 | ||||
| Negative | Reference | 1 | Reference | 1 | ||
| Positive | 0.527 | 0.473–0.587 | <0.001 | 0.527 | 0.448–0.619 | <0.001 |
| PR | <0.001 | <0.001 | ||||
| Negative | Reference | 1 | Reference | 1 | ||
| Positive | 0.539 | 0.535–0.658 | <0.001 | 0.756 | 0.647–0.882 | <0.001 |
| HER2 | <0.001 | <0.001 | ||||
| Negative | Reference | 1 | Reference | 1 | ||
| Positive | 0.729 | 0.647–0.821 | <0.001 | 0.608 | 0.535–0.692 | <0.001 |