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. 2023 Jan 16;16(1):130. doi: 10.3390/ph16010130

Table 1.

ROB2 assessment for each randomized clinical trial regarding the association of vitamin D supplementation with ICU admission and risk of death. Green indicates a low risk of bias; yellow indicates some concerns for risk of bias; red indicates a high risk of bias.

ROB2: A Revised Cochrane Risk-of-Bias Tool for Randomized Trials
R D Mi Me S O
Sabico (2021) [32] graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i002.jpg graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i002.jpg graphic file with name pharmaceuticals-16-00130-i002.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg
Castillo (2020) [36] graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i002.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg
Torres (2022) [37] graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i002.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg graphic file with name pharmaceuticals-16-00130-i002.jpg graphic file with name pharmaceuticals-16-00130-i002.jpg graphic file with name pharmaceuticals-16-00130-i002.jpg
Murai (2021) [26] graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i001.jpg
Nogues (2021) [38] graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg graphic file with name pharmaceuticals-16-00130-i001.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg graphic file with name pharmaceuticals-16-00130-i003.jpg

Legend: R—bias arising from the randomization process; D—bias due to deviations from intended interventions; Mi—bias due to missing outcome data; Me—bias in measurement of the outcome; S—bias in selection of the reported results; O—overall risk of bias; + Inline graphic low risk of bias; − Inline graphic high risk of bias; ? Inline graphic some concerns.