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. 2023 Jan 15;15(1):245. doi: 10.3390/v15010245

Figure 3.

Figure 3

Time-scaled maximum-likelihood phylogenetic tree with viral sequences from companion animals and owners of households USZ22, USZ29, USZ36, USZ38, and USZ39. A total of 330 sequences are included to represent the genetic diversity of the SARS-CoV-2 Delta variant in Zurich from November 2021 to January 2022 and the genetic diversity of the SARS-CoV-2 Delta variant in companion animals worldwide (see Materials and Methods Section for a detailed description of the alignment). Sequences from the study and companion animals are indicated with a dot in the tree; only sequences from the study are labeled with the sample name and pangolin lineage. Tip color indicates the location of the sequence. Time scale is shown at the bottom of the figure; a clock rate of 0.0008 substitutions/site/year is assumed for the reconstruction of the time-scaled tree. Branch length in the tree represents evolutionary distance, i.e., substitutions per site. Reference sequence Wuhan/Hu-1/2019 is used as an outgroup to root the tree.