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. 2022 Dec 28;15(1):83. doi: 10.3390/v15010083

Figure 3.

Figure 3

Phylogenetic reconstruction of VACV-Wyeth clones A111, A211, and A311. A multialignment of the conserved region of 38 orthopoxvirus genomes was used to infer a maximum likelihood tree using MEGA X, opting for the General Time Reversible (GTR) model and five-category discrete gamma distributed with invariant site. Numbers next to branch nodes indicate the percentage of 1000 replicates of bootstrap support (values >70 are shown). The scale bar indicates the number of substitutions per site. Colored boxes indicate the three main clades in the vaccinia group. The Wyeth clones are indicated with red circles.