Table 4.

Mono-culture approach for the microbial production of flavonoids.

Substrate	Product	Host Strain	Titer (mg/L)	References
Glucose	Naringenin	Y. lipolytica	252.4	[130]
Glucose	Eriodictyol	Y. lipolytica	134.2	[130]
Glucose	Taxifolin	Y. lipolytica	110.5	[130]
Genistein	4′-O-methyl genistein	E. coli	46.81	[147]
Daidzein	4′-O-methyl daidzein	E. coli	102.88	[147]
Naringenin	Kaempferol	E. coli	1184.2	[153]
Naringenin	Astragalin	E. coli	1738.5	[153]
Hesperetin	Hesperetin-3′-O-rhamnoside	E. coli	2400	[151]
Quercetin	Quercitrin	E. coli	4300	[151]
Kaempferol	Afzelin	E. coli	1900	[151]
Catechin and Glucose	Cyanidin 3-O-glucoside	E. coli	439	[154]
Tyrosine	Scutellarein	E. coli	106.2	[155]
Phenylalanine	Baicalein	E. coli	23.6	[155]
Naringenin	Genistein	E. coli	35	[128]
p-Coumaric acid	Genistein	E. coli	18.6	[128]
Tyrosine and malonate	Naringenin	E. coli	191.9	[177]
Apigenin	Isovitexin	E. coli	3772	[178]
Luteolin	Isoorientin	E. coli	3820	[178]
Catechin	Cyanidin 3-O-glucoside	C. glutamicum	40	[139]
Sucrose and glycerol	Naringenin	S. cerevisiae	28.68	[18]
Glucose	Kaempferol	S. cerevisiae	86	[159]
Xylose	p-Coumaric acid	S. cerevisiae	242	[2]
Glucose	Delphinidin 3-O-glucoside	S. cerevisiae	1.86	[179]
Glucose	Cyanidin 3-O-glucoside	S. cerevisiae	1.55	[179]
Glucose	Pelargonidin 3-O-glucoside	S. cerevisiae	0.85	[179]
Glucose	Icaritin	S. cerevisiae	7.2	[180]
Glucose	Taxifolin	S. cerevisiae	336.8	[181]
Green tea	Anthocyanin	L. lactis	1.5	[157]