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The predicted ADMET characteristics for venetoclax and the saquayamycin F (NPA002200).
| Compound Name/Code | Absorption (A) |
Distribution (D) | Metabolism (M) |
Excretion (E) |
Toxicity (T) |
|
|---|---|---|---|---|---|---|
| Caco2 Permeability | Human Intestinal Absorption (HIA) | Log BB | CYP3A4 Inhibitor/Substrate | Total Clearance | AMES Toxicity | |
| Venetoclax | 0.847 | 100 | –1.9 | Yes | –0.096 | No |
| Saquayamycin F (NPA002200) | 0.271 | 80.9 | 0.27 | Yes | –0.196 | No |
