Figure 1.

Distribution of the number of mutational events in the monkeypox genome sequences analyzed. (A) The average number of mutations per sample is 38.35 worldwide. (B) The mutations per sample of the MPXV outbreaks in 2021 and 2022. (C) The mutation events per country. (D) The distribution of the number of mutations for each sample per continent. (E) The maximum likelihood phylogenetic tree of the nucleotide sequences of the whole-genome MPXV strains selected from the collection date of 1962 to 2022 from the GISAID database across the world. The human MPXV genomes belong to clade IIb. The phylogenetic analysis was conducted using the maximum likelihood method with 1000 bootstraps.