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. 2023 Jan 7;24(2):1221. doi: 10.3390/ijms24021221

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Ovarian cancer patient outcome based on combined low and high expression of E2- and E1-synthetizing HSD17B enzymes, respectively. (A–D) Kaplan–Meier curves comparing the correlation between low intratumoural expression levels of the E2-synthetizing enzymes HSD17B1 (A), HSD17B5 (B), HSD17B7 (C) and HSD17B12 (D); combined with high intratumorual expression of the different E1-synthetizing HSD17B isoforms indicated, including HSD17B2, HSD17B4, HSD17B6, HSD17B10 and HSD17B14; and PPS, PFS and OS in ovarian cancer patients.