Table 1.
Patients’ (n = 67) results of clinical, biochemical and ICSI cycles. All data are shown as average (±) and SD and medians (from min. to max.) or continuous variables and as n° and proportions (%). Mann–Whitney U test was not otherwise specified, independent sample t test and χ2 Chi-squared test. 1 BMI = Body Mass Index; 2 LH = Luteinizing Hormone. The underlines highlight the statistical significance.
| Abnormal Response | Normal Response | p Value | |||
|---|---|---|---|---|---|
| Proportions (%) | 31 (46.30) | 36 (53.70) | |||
| Age (years) | 35.16 ± 3.75 | 35 (28 to 42) | 35.25 ± 3.75 | 35.50 (28 to 42) | 0.92 |
| BMI (Kg/m2) 1 | 22.79 ± 3.72 | 21.80 (17.40 to 34.10) | 22.43 ± 3.14 | 22.20 (16 to 29.40) | 0.93 |
| AMH (ng/mL) | 3.25 ± 3.13 | 2.59 (0.84 to 17.60) | 3.10 ± 3.75 | 1.89 (0.24 to 18.09) | 0.11 |
| Total FSH (IU) | 2464.96 ± 1175.40 | 2100 (1109 to 5100) | 2342.32 ± 1139.76 | 2211 (721.50 to 5100) | 0.26 |
| FSH (mIU/mL) | 8.01 ± 3.23 | 7.60 (1.76 to 15.7) | 8.24 ± 4.97 | 7.64 (0.35 to 26.28) | 0.72 |
| LH (mIU/mL) 2 | 5.57 ± 2.56 | 4.84 (2.29 to 12.13) | 6.08 ± 2.74 | 5.80 (0.83 to 11.81) | 0.30 |
| AFC (n) | 12.7 ± 5.31 | 13 (3 to 26) | 12.30 ± 5.69 | 11.50 (3 to 25) | 0.76 |
| E2 (pg/mL) | 1399.12 ± 883.69 | 1130 (423 to 4433) | 1466 ± 952.40 | 1130 (361 to 4433) | 0.85 |
| Progest. (ng/dL) | 0.86 ± 0.38 | 0.78 (0.2 to 1.75) | 1.00 ± 0.89 | 0.81 (0.3 to 5.13) | 0.90 |
| Length of Treatment (days) | 11.32 ± 1.92 | 11.00 (7 to 17) | 10.97 ± 1.54 | 11.00 (8 to 15) | 0.41 |
| Injected Oocytes (n) | 5.19 ± 2.34 | 5.00 (1 to 10) | 7.03 ± 4.4 | 7.00 (1 to 17) | 0.11 |
| Fertil. Oocytes (n) | 4.03 ± 1.72 | 4.00 (1 to 7) | 5.81 ± 3.75 | 6.50 (1 to 13) | 0.03 |
| Embr. Obtained (n) | 3.00 ± 1.26 | 3.00 (1 to 6) | 3.94 ± 2.68 | 3.50 (0 to 10) | 0.29 |
| Embr. Transferred (n) | 1.74 ± 0.82 | 2.00 (0 to 3) | 1.64 ± 0.64 | 2.00 (0 to 3) | 0.32 |
| Pregnancy Status | Abnormal Response | Normal Response | |||
| Yes | 7 (22.6) | 10 (27.80) | 0.62χ2 | ||
| No | 24 (77.4) | 26 (72.2) | |||
| Polymorphism of FSH-R | Abnormal Response | Normal Response | |||
| Asn/Asn Absent Polymorphism | 7 (22.6) | 23 (63.9) | <0.01χ2 | ||
| Asn/Ser Heterozygote | 17 (54.8) | 9 (25) | |||
| Ser/Ser Homozygote | 7 (22.6) | 4 (11.1) | |||